netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
Notes:
Please also refer to the Cancer Drugs Fund list
 Details...
08.03.04.02  Expand sub section  Prostate cancer and gonadorelin analogues
08.03.04.02  Expand sub section  Gonadorelin analogues
08.03.04.02  Expand sub section  Anti-androgens
Leuprorelin acetate prolonged release injection (prostate cancer)

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First Choice
Amber 1
Initiation on recommendation of consultant specialist only

Hospital use = one month injection only (3.75mg)

First-line gonadorelin analogue for use in prostate cancer
Abiraterone tabs

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Formulary
High Cost Medicine
Red
Blueteq prior approval required

Link  NICE TA259: Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen
Link  NICE TA387: Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated    
Bicalutamide tabs

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Formulary
Amber 1
   
Buserelin injection, nasal spray (Suprefact - prostate cancer)

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Formulary
Red
For prostate carcinoma
   
Cyproterone acetate tabs

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Formulary
Amber 2
   
Enzalutamide caps

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Formulary
High Cost Medicine
Red

Link  NICE TA316: Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimen
Link  NICE TA377: Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated    
Flutamide tabs

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Formulary
Amber 2
   
Goserelin implant (prostate cancer)

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Formulary
Amber 1
Initiation on recommendation of consultant specialist only

Hospital use = one month injection only (3.6mg)
   
Triptorelin SR injection (prostate cancer)

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Formulary
Amber 1
Initiation on recommendation of consultant specialist only

Hospital use = one month injection only
   
 ....
Key
note Notes First Choice Item First Choice item
Section Title Section Title (top level) Non Formulary Item Non Formulary section
Section Title Section Title (sub level)
Cytotoxic Drug
Cytotoxic Drug
Restricted Drug
Restricted Drug
CD
Controlled Drug
Unlicensed Drug
Unlicensed
High Cost Medicine
High Cost Medicine
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Link to SPCs
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Link to adult BNF
Track Changes
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Cancer Drugs Fund
Cancer Drugs Fund
   

 

Traffic Light Status Information

Status Description
  Red   Specialist Prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   
  Amber 1   Treatment can be initiated in primary care after a recommendation from an appropriate specialist  
  Amber 2   Specialist initiation followed by maintenance prescribing in primary care  
  Amber 3   Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  
  Green   Specialist and non-specialist initiation  
  Grey   Not recommended for prescribing  

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