netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
 Search
 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
Notes:

Please also refer to the Cancer Drugs Fund list

Where a formulary entry does not detail a medicine’s indications for use, the medicine can be assumed to be approved for all licensed indications.

Formulary approved "off-label" use is detailed separately.

 Details...
08.02.01  Expand sub section  Antiproliferative immunosuppressants
Cytotoxic Drug Azathioprine tabs (neurology indications, including off-label use)
View adult BNF View SPC online
Formulary
Amber 3

Refer to SE London immunomodulatory shared care guidance for list of indications (link below at end of BNF section)

 
   
Ciclosporin caps, oral solution (neurology indications - off-label)
View adult BNF View SPC online
Formulary
Amber 3

Refer to SE London immunomodulatory shared care guidance for list of indications (link below at end of BNF section)

 
   
Hydroxychloroquine tabs (neurology indications - off-label)
View adult BNF View SPC online
Formulary
Amber 3

Refer to SE London immunomodulatory shared care guidance for list of indications (link below at end of BNF section)

 
   
Leflunomide tabs (neurology indications - off-label)
View adult BNF View SPC online
Formulary
Amber 3

Refer to SE London immunomodulatory shared care guidance for list of indications (link below at end of BNF section)

 
   
Cytotoxic Drug Methotrexate tabs (neurology indications - off-label)
View adult BNF View SPC online
Formulary
Amber 3

Refer to SE London immunomodulatory shared care guidance for list of indications (link below at end of BNF section)

 
   
Mycophenolate mofetil tabs, caps, suspension (neurology indications - off-label)
View adult BNF View SPC online
Formulary
Amber 3

Refer to SE London immunomodulatory shared care guidance for list of indications (link below at end of BNF section)

 
   
Cytotoxic Drug Azathioprine tabs (liver transplant)
View adult BNF View SPC online
Formulary

Immunosuppression in liver transplant Red Traffic Light for new patients

Amber Traffic Light for patients currently receiving prescriptions in primary care (see shared care link below)

 
Link  SE London APC Shared Care Guideline: Azathioprine in adult liver transplant patients
   
Cytotoxic Drug Azathioprine tabs, injection (renal transplant)
View adult BNF View SPC online
Formulary
Red

Immunosuppression in renal transplant

10mg capsules are also available for patients who require smaller doses (unlicensed product).

 
   
Mycophenolate mofetil tabs, caps, suspension, injection (liver transplant)
View adult BNF View SPC online
Formulary

Imunnosupressant in liver transplant patients Red Traffic Light for new patients

Amber Traffic Light for patients currently receiving prescriptions in primary care (see shared care link below)

 
Link  SE London APC Shared Care Guidance: Mycophenolate mofetil in liver transplant patients
   
Mycophenolate mofetil tabs, caps, suspension, injection (renal transplant)
View adult BNF View SPC online
Formulary
Red

Imunnosupressant in renal transplant patients

 
Link  NICE TA481: Immunosuppressive therapy for kidney transplant in adults
Link  NICE TA482: Immunosuppressive therapy for kidney transplant in children and young people
   
Mycophenolate sodium tablets (renal transplant)
View adult BNF View SPC online
Restricted Drug Restricted
Red
High Cost Medicine

Only approved for continuing treatment of renal transplant patients

Prescribers who want to initiate mycophenolic acid for other indications must first discuss with, and get agreement from, the patient’s GP about arrangements for ongoing prescribing

 
   
Mepacrine tabs (discoid lupus)
View adult BNF
Unlicensed Drug Unlicensed
Red

Discoid lupus erythematosus (lupus consultants only)

Dose: from 50 mg three times a week to a maximum dose of 100 mg three times a day

PIL available on GTi at GSTFT

 
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Specialist or hospital prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist or hospital. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   

Amber 1

Treatment can be initiated in primary care after a recommendation from an appropriate specialist  

Amber 2

Specialist initiation followed by maintenance prescribing in primary care  

Amber 3

Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  

Green

Specialist and non-specialist initiation  

Grey

Not recommended for prescribing  

netFormulary