netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 5: Infections - Full Chapter
Notes:
This section advises on the choice of anti-infective agents available at each Trust.  Doctors should refer to local or departmental antibiotic  guidelines for advice regarding specific treatments within specialised  units (including prophylaxis for surgical, medical and dental  procedures). Different antibiotic policies can be found in different  hospitals due to local variations in resistance and antibiotic  susceptibility.

M: Use of this agent only to be initiated under the advice of a  microbiologist or virologist as appropriate.

S: Use of this agent only to be initiated under the advice of a relevant clinical specialist.
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05.04.01  Expand sub section  Antimalarials
Artesunate injection

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Restricted Drug Unlicensed
Red
At GSTFT, use in accordance with the guideline “Management of Malaria in Adults”

First-line therapy for severe falciparum malaria in non-pregnant adults
   
05.04.01  Expand sub section  Artemether with lumefabtrine
Artemether with lumefantrine tabs (Riamet®)

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Formulary
   
05.04.01  Expand sub section  Chloroquine
Chloroquine tabs, syrup, injection

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Formulary Injection = Red Traffic Light 
   
05.04.01  Expand sub section  Mefloquine
Mefloquine tabs

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05.04.01  Expand sub section  Primaquine to top
Primaquine tabs

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Primaquine tabs

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Restricted Drug Unlicensed Prevention of subsequent relapse of non-falciparum malaria
Dose: Orally 15 mg daily for 14 days following the treatment of P. vivax and P. ovale malaria.

Please seek expert advice for G6PD deficient individuals and cases where relapse occurs despite primaquine therapy
   
Primaquine tabs

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Restricted Drug Unlicensed PCP treatment in accordance with BHIVA guidelines
Dose: 15-30 mg once daily
   
05.04.01  Expand sub section  Proguanil
Proguanil hydrochloride tabs

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Proguanil hydrochloride with atovaquone tabs

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05.04.01  Expand sub section  Pyrimethamine
Fansidar® tabs (pyrimethamine and sulfadoxine)

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05.04.01  Expand sub section  Quinine
Quinine dihydrochloride injection

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Red
   
Quinine sulphate tabs

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05.04.01  Expand sub section  Tetracyclines
Doxycycline caps

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 ....
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Section Title Section Title (top level) Non Formulary Item Non Formulary section
Section Title Section Title (sub level)
Cytotoxic Drug
Cytotoxic Drug
Restricted Drug
Restricted Drug
CD
Controlled Drug
Unlicensed Drug
Unlicensed
High Cost Medicine
High Cost Medicine
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Cancer Drugs Fund
Cancer Drugs Fund
   

 

Traffic Light Status Information

Status Description
  Red   Specialist Prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   
  Amber 1   Treatment can be initiated in primary care after a recommendation from an appropriate specialist  
  Amber 2   Specialist initiation followed by maintenance prescribing in primary care  
  Amber 3   Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  
  Green   Specialist and non-specialist initiation  
  Grey   Not recommended for prescribing  

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