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Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 5: Infections - Full Chapter
Notes:
This section advises on the choice of anti-infective agents available at each Trust.  Doctors should refer to local or departmental antibiotic  guidelines for advice regarding specific treatments within specialised  units (including prophylaxis for surgical, medical and dental  procedures). Different antibiotic policies can be found in different  hospitals due to local variations in resistance and antibiotic  susceptibility.

M: Use of this agent only to be initiated under the advice of a  microbiologist or virologist as appropriate.

S: Use of this agent only to be initiated under the advice of a relevant clinical specialist.
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05.03.01  Expand sub section  HIV infection
05.03.01  Expand sub section  Nucleoside reverse transcriptase inhibitors
Abacavir tabs, oral solution

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High Cost Medicine
Red
   
Abacavir with lamiviudine (generic - Kivexa brand no longer stocked)

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High Cost Medicine
Red
   
Atripla tabs  (tenofovir disoproxil with emtricitabine and efavirenz)

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High Cost Medicine
Red
No longer stocked. Prescribe Truvada (tenofovir disoproxil and emtricitabine) and efavirenz as separate preparations
   
Combivir tabs (zidovudine and lamivudine)

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High Cost Medicine
Red
   
Descovy tabs (emtricitabine with tenofovir alafenamide)

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High Cost Medicine
Red

Link  NHSE 16043/P: Clinical Commissioning Policy: Tenofovir Alafenamide for treatment of HIV 1 in adults and adolescents    
Didanosine tabs, caps

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High Cost Medicine
Red
   
Emtricitabine caps, oral solution

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High Cost Medicine
Red
   
Eviplera (tenofovir disoproxil with emtricitabine and rilpivirine)

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High Cost Medicine
Red
   
Genvoya tabs (elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide)

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High Cost Medicine
Red

Link  MHRA Dec 2016: Cobicistat, ritonavir and coadministration with a steroid: risk of systemic corticosteroid adverse effects
Link  NHSE 16043/P: Clinical Commissioning Policy: Tenofovir Alafenamide for treatment of HIV 1 in adults and adolescents    
Lamivudine tabs, oral solution

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High Cost Medicine
Red
   
Odefsey tabs (emtricitabine with rilpivirine and tenofovir alafenamide)

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High Cost Medicine
Red

Link  NHSE 16043/P: Clinical Commissioning Policy: Tenofovir Alafenamide for treatment of HIV 1 in adults and adolescents    
Stavudine caps, oral solution

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High Cost Medicine
Red
   
Stribild tabs (tenofovir disoproxil with cobicistat, elvitegravir and emtricitabine)

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Formulary
High Cost Medicine
Red

Link  MHRA Dec 2016: Cobicistat, ritonavir and coadministration with a steroid: risk of systemic corticosteroid adverse effects    
Tenofovir disoproxil tabs (Viread)

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High Cost Medicine
Red

Link  NICE CG165: Hepatitis B (chronic) - incorporates TA173
Link  NICE TA173: Hepatitis B (chronic) - tenofovir disoproxil    
Triumeq tabs (dolutegravir, abacavir & lamivudine)

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High Cost Medicine
Red
   
Trizivir tabs (abacavir, lamivudine and zidovudine)

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High Cost Medicine
Red
   
Truvada tabs  (tenofovir disoproxil with emtricitabine)

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High Cost Medicine
Red
   
Zidovudine caps, oral solution

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Formulary
High Cost Medicine
Red
   
05.03.01  Expand sub section  Protease inhibitors
05.03.01  Expand sub section  Non-nucleoside reverse transcriptase inhibitors
05.03.01  Expand sub section  Other antiretrovirals to top
05.03.01  Expand sub section  Pharmacokinetic enhancers of antiretrovirals
05.03.01  Expand sub section  Combination Products
 ....
Key
note Notes First Choice Item First Choice item
Section Title Section Title (top level) Non Formulary Item Non Formulary section
Section Title Section Title (sub level)
Cytotoxic Drug
Cytotoxic Drug
Restricted Drug
Restricted Drug
CD
Controlled Drug
Unlicensed Drug
Unlicensed
High Cost Medicine
High Cost Medicine
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Cancer Drugs Fund
Cancer Drugs Fund
   

 

Traffic Light Status Information

Status Description
  Red   Specialist Prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   
  Amber 1   Treatment can be initiated in primary care after a recommendation from an appropriate specialist  
  Amber 2   Specialist initiation followed by maintenance prescribing in primary care  
  Amber 3   Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  
  Green   Specialist and non-specialist initiation  
  Grey   Not recommended for prescribing  

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