netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 Formulary Chapter 4: Central nervous system - Full Chapter
In this section "SPECIALISTS" refer to medical prescribers specialising in Mental Health unless otherwise stated. At Guy's and St Thomas' and Lewisham Hospitals this would refer to SLAM employed consultants
04.07.01  Expand sub section  Non-opioid analgesics and compound analgesic preparations
Aspirin tabs
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Dilofenac sodium tabs, m/r tabs, dispersible tabs, suppositories
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Link  MHRA Jun 2013: Diclofenac: new contraindications and warnings
Ibuprofen tabs, suspension
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Link  MHRA Jun 2015: High-dose ibuprofen (≥2400mg/day): small increase in cardiovascular risk
Nefopam tabs
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Paracetamol injection
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Restricted to short-term treatment of moderate pain and fever when administration by the intravenous route is clinically justified

For patients weighing less than 50 kg:

  • Max dose = 15 mg/kg
  • Minimum dose interval of 4 hours
  • Maximum daily dose must not exceed 60 mg/kg (without exceeding 3g)

 In severe renal insufficiency (creatinine clearance ≤30 mL/min):

  • Minimum dose interval of 6 hours

Not to exceed 3g as total daily dose in the following patients:

  • Hepatocellular insufficiency
  • Chronic alcoholism
  • Chronic malnutrition or dehydration
Paracetamol tabs, soluble tabs, oral suspension, suppositories
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04.07.01  Expand sub section  Compound analgesic preparations
Co-codamol tabs, dispersible tabs (paracetamol and codeine)
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Formulary Strengths available:
  • Co-codamol 8/500
  • Co-codamol 30/500 
    Co-dydramol 10/500 tabs (paracetamol and dihydrocodeine)
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    note Notes
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    Traffic Light Status Information

    Status Description


    Specialist or hospital prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist or hospital. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   

    Amber 1

    Treatment can be initiated in primary care after a recommendation from an appropriate specialist  

    Amber 2

    Specialist initiation followed by maintenance prescribing in primary care  

    Amber 3

    Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  


    Specialist and non-specialist initiation  


    Not recommended for prescribing