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Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
Notes:

Where a formulary entry does not detail a medicine’s indications for use, the medicine can be assumed to be approved for all licensed indications.

Formulary approved "off-label" use is detailed separately.

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 Details...
02.09  Expand sub section  Antiplatelet drugs
Abciximab injection
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Formulary
Red
USE UNDER SPECIALIST SUPERVISION ONLY Use as per NICE CG94: ACS and NSTEMI (see link below at end of section) 
   
Aspirin (antiplatelet) tabs
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Formulary  
   
Cangrelor injection
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Restricted Drug Restricted
Red

Approved for use (in combination with aspirin suppositories) for the reduction of thrombotic cardiovascular events in patients with coronary artery disease undergoing PCI.

Restricted to unconscious patients in whom oral therapy with P2Y12 inhibitors (e.g. clopidogrel) is not feasible.

 

 
   
Clopidogrel tabs
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Formulary Use as per NICE CG94: ACS and NSTEMI (see link below at end of section) Use as per NICE TA210: Prevention of occlusive vascular events (see link below at end of section) 
   
Dipyridamole tabs, m/r caps, oral suspension
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Formulary Use as per NICE TA210: Prevention of occlusive vascular events (see link below at end of section) 
   
Eptifibatide injection
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Formulary
Red
USE UNDER SPECIALIST SUPERVISION ONLY Use as per NICE CG94: ACS and NSTEMI (see link below at end of section) 
   
Prasugrel tabs
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Formulary  
Link  NICE TA317: Prasugrel with PCI for ACS (review of TA182)
   
Ticagrelor tabs, orodispersible tabs
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Formulary
Amber 1

Orodispersible tabs reserved for patients with swallowing difficulties or on enteral feeding

 
Link  NICE TA236: Acute coronary syndromes - ticagrelor
Link  NICE TA420: Ticagrelor for preventing atherothrombotic events after myocardial infarction
   
Tirofiban injection
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Formulary
Red

USE UNDER SPECIALIST SUPERVISION ONLY

Use as per NICE CG94: ACS and NSTEMI (see link below at end of section) Use for reduction of cardiovascular events in patients with STEMI intended for primary PCI

 

Refer to local guidelines for use

 
   
Aspirin suppositories
(Unlicensed product)
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Unlicensed Drug Unlicensed Where treatment is imperative and oral treatment is not possible 
   
Ticlopidine tabs
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Unlicensed Drug Unlicensed Intolerance to aspirin or clopidogrel. Dose: 250 mg bd 
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Specialist or hospital prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist or hospital. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   

Amber 1

Treatment can be initiated in primary care after a recommendation from an appropriate specialist  

Amber 2

Specialist initiation followed by maintenance prescribing in primary care  

Amber 3

Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  

Green

Specialist and non-specialist initiation  

Grey

Not recommended for prescribing  

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