netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.08.02  Expand sub section  Oral anticoagulants
Acenocoumarol tabs
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Amber 2
 
   
Apixaban tabs
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Amber Traffic Light For treatment and secondary prevention of DVT and PE, and thromboprophylaxis in AF.

See links at the end of the section for initiation of treatment and transfer of care documents

Red Traffic Light (hospital only) For prevention of VTE after hip or knee replacement surgery 

 
Link  SE London APC prescribing guidance - Apixaban for AF
Link  SE London APC prescribing guidance - Apixaban for VTE
Link  NICE TA245: Venous thromboembolism - apixaban (hip and knee surgery
Link  NICE TA275: Stroke and systemic embolism (prevention, non-valvular atrial fibrillation) - apixaban
Link  NICE TA341: Apixaban for treatment and secondary prevention of DVT and/or PE
Link  Apixaban for non-valvular AF - manufacturers patient information booklets (several languages)
Link  Apixaban for venous thromboembolism - manufaturers patient information booklets (several languages)
   
Dabigatran caps
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Amber Traffic Light For treatment and secondary prevention of DVT and PE, and thromboprophylaxis in AF

See links at the end of the section for initiation of treatment and transfer of care documents

 

Red Traffic Light (hospital only) For prevention of VTE after hip or knee replacement surgery 

 
Link  SE London APC prescribing guidance: Dabigatran for AF
Link  SE London APC prescribing guidance: Dabigatran for VTE
Link  NICE TA157: Venous thromboembolism - dabigatran
Link  NICE TA249: Dabigatran for Stroke prevention in AF
Link  NICE TA327: Dabigatran for treatment and secondary prevention of DVT and/or PE
   
Edoxaban tabs
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Amber 3
See links at the end of the section for initiation of treatment and transfer of care documents 
Link  SE London APC prescribing guidance: Edoxaban for AF
Link  SE London APC prescribing guidance: Edoxaban for VTE
Link  NICE TA354: Edoxaban for treating and for preventing DVT and/or PE
Link  NICE TA355: Edoxaban for thromboprohylaxis in non-valvular AF
Link  Edoxaban - manufacturer’s patient support materials (several languages)
   
Phenindione tabs
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Amber 2
 
   
Rivaroxaban tabs (licensed uses)
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Amber Traffic Light For treatment and secondary prevention of DVT and PE, thromboprophylaxis in AF, and preventing adverse outcomes after acute management of ACS.

See links at the end of the section and below for initiation of treatment and transfer of care documents

 

Red Traffic Light (hospital only) For prevention of VTE after elective hip or knee replacement surgery

 
Link  Rivaroxaban for ACS: Notification of initiation to GP
Link  Rivaroxaban in ACS: Transfer of care to GP
Link  SE London prescribing guidance: Rivaroxaban for ACS
Link  SE London prescribing guidance: Rivaroxaban for AF
Link  SE London prescribing guidance: Rivaroxaban for VTE
Link  NICE TA256: Rivaroxaban for thromboprophylaxis in AF
Link  NICE TA261: Rivaroxaban for the treatment of DVT and prevention of recurrent DVT and/or PE
Link  NICE TA287: Rivaroxaban for treating PE and preventing recurrent VTE
Link  NICE TA335: Rivaroxaban for preventing adverse outcomes after acute management of ACS
Link  Rivaroxaban - manufacturer’s patient brochures (several languages)
   
Warfarin tabs
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Amber 2
 
   
Rivaroxaban tabs (orthopaedic off label use)
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Red
Approved off-label indication:
  • Thromboprophylaxis post pelvic ring/acetabular fracture as an alternative to Low Molecular Weight Heparin Full course of up to 90 days to be prescribed and provided by the hospital. Dose as per thromboprophylaxis post elective orthopaedic surgery (10mg daily)  
  • Link  SE London APC Recommendation: Rivaroxaban for thromboprophylaxis post pelvic ring fracture
       
     ....
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to SPCs
    SMC
    Scottish Medicines Consortium
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Red

    Specialist or hospital prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist or hospital. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   

    Amber 1

    Treatment can be initiated in primary care after a recommendation from an appropriate specialist  

    Amber 2

    Specialist initiation followed by maintenance prescribing in primary care  

    Amber 3

    Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  

    Green

    Specialist and non-specialist initiation  

    Grey

    Not recommended for prescribing  

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