netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.08.01  Expand sub section  Parenteral anticoagulants
Argatroban injection

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Formulary For use under the supervision of a Consultant Haematologist
For anticoagulation in patients with HIT type 2 undergoing cardiac surgery or have renal failure in a HDU/ITU setting who are not suitable for treatment with fondaparinux
   
Defibrotide infusion

Restricted Drug Unlicensed
High Cost Medicine
Red
USE UNDER SPECIALIST SUPERVISION ONLY
Treatment of patients with severe veno-occlusive disease following stem cell transplant in line with NHS England Clinical Commissioning Policy B04/P/c

Blueteq prior approval required

Link  NHS England Clinical Commissioning Policy B04/P/c: Defibrotide in severe venoocclusive disease following stem cell transplant    
02.08.01  Expand sub section  Heparin
Heparin injection

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Formulary
   
02.08.01  Expand sub section  Low molecular weight heparins
Enoxaparin injection

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Formulary
Amber 2
   
Dalteparin injection

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Formulary
Red
First-line LMWH at GSTFT
   
02.08.01  Expand sub section  Hirudins
Bivalirudin injection

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Formulary
Red

Link  NICE CG94: Unstable angina and NSTEMI
Link  NICE TA230 : Bivalirudin for the treatment of STEMI, 2011    
02.08.01  Expand sub section  Epoprostenol to top
Epoprostenol injection

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Formulary
High Cost Medicine
Red
USE ON SPECIALIST ADVICE ONLY
   
02.08.01  Expand sub section  Fondaparinux
Fondaparinux injection

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Formulary
Red
Use in accordance with NICE CG92: Venousthromboembolism: reducing the risk

Approved off-label indication:
First-line parenteral anticoagulant in adult patients with HIT and patients with an allergy to heparin
Use in accordance with local guideline
   
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Key
note Notes First Choice Item First Choice item
Section Title Section Title (top level) Non Formulary Item Non Formulary section
Section Title Section Title (sub level)
Cytotoxic Drug
Cytotoxic Drug
Restricted Drug
Restricted Drug
CD
Controlled Drug
Unlicensed Drug
Unlicensed
High Cost Medicine
High Cost Medicine
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Link to adult BNF
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Cancer Drugs Fund
Cancer Drugs Fund
   

 

Traffic Light Status Information

Status Description
  Red   Specialist Prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   
  Amber 1   Treatment can be initiated in primary care after a recommendation from an appropriate specialist  
  Amber 2   Specialist initiation followed by maintenance prescribing in primary care  
  Amber 3   Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  
  Green   Specialist and non-specialist initiation  
  Grey   Not recommended for prescribing  

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