netFormulary South East London Joint Medicines Formulary NHS
Guy's and St Thomas' NHS Foundation Trust
Kings College Hospital NHS Foundation Trust
Lewisham and Greenwich NHS Trust
 
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 Formulary Chapter 11: Eye - Full Chapter
11.03.02  Expand sub section  Antifungals
Natamycin 5% eye drops
First Choice
Red
First line empiric management of fungal keratitis Unlicensed preparation Usual dosing schedule = one drop hourly day and night for 48 hours, then one drop hourly during the day time, gradually reduced to four times a day. Usual course length 1 month.  
Chlorhexidine 0.2% eye drops
Unlicensed Drug Unlicensed
Red
Additional topical treatment for fungal keratitis where there has been insufficient response to natamycin eye drops Usual dosing schedule = one drop hourly day and night for 48 hours, then one drop hourly during the day time, gradually reduced to four times a day. Usual course length 1 month.  
   
Amphotericin 0.15% eye drops
Unlicensed Drug Unlicensed
Red
For fungal keratitis with confirm/suspected candida infection  
   
Amphotericin 5 micrograms intravitreal injection
Unlicensed Drug Unlicensed
Red
Acute treatment of candida/fungal endogenous endophthalmitis  
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Specialist or hospital prescribing only. The responsibility for prescribing, monitoring, dose adjustment and review should remain with the specialist or hospital. In very exceptional circumstances a specialist may discuss individual patient need for a RED drug to be prescribed by a GP and the GP should consider informing the Medicines Management team before a decision is made to prescribe for individual patients.   

Amber 1

Treatment can be initiated in primary care after a recommendation from an appropriate specialist  

Amber 2

Specialist initiation followed by maintenance prescribing in primary care  

Amber 3

Specialist initiation with ongoing monitoring required. After dose stabilisation GPs can be requested to take over prescribing responsibilities using the approved APC shared care documentation  

Green

Specialist and non-specialist initiation  

Grey

Not recommended for prescribing  

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